EPIGENETIC AGE ACCELERATION AND METHYLATION DIFFERENCES IN IGG4-RELATED CHOLANGITIS AND PRIMARY SCLEROSING CHOLANGITIS

Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis

Abstract Background IgG4-related cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC) are chronic fibro-inflammatory hepatobiliary conditions, with genetic, environmental, and immunologic risk factors, in which Boots epigenetic alterations may provide insights into pathophysiology and novel biomarkers.This study is the first to assess met

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Measuring customer satisfaction with the Gautrain during the COVID-19 pandemic using the service quality model

Background: The Gautrain was created with the sole purpose of availing efficient transportation between the three metropolitan municipalities, namely the City of Tshwane, the City of Johannesburg and the City of Ekurhuleni.The Gautrain has been transporting more than five million passengers annually.However, ridership decreased drastically Fruit Te

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Biomarkers in the Cerebrospinal Fluid of Patients with Psychotic Disorders Compared to Healthy Controls: A Systematic Review and Meta-Analysis

Introduction Biomarkers in CSF could provide etiological clues and diagnostic tools for psychotic disorders.However, an overview of all CSF findings in individuals with psychotic disorders compared to healthy controls is lacking.Objectives To analyse CSF findings from individuals with psychotic disorders compared to healthy controls.Methods PubMed,

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